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    1 

    Zhu, Y., Zhang, Q., Shi, X., & Han, D. Hierarchical Hydrogel Composite Interfaces with Robust Mechanical Properties for Biomedical Applications [J]. Advanced Materials,2019. 

    https://onlinelibrary.wiley.com/cms/attachment/aa64f176-99a3-4e75-a078-bb77673ee929/adma201804950-fig-0003-m.jpg 

    2 

    Liu, S., Nie, Y., Zhang, Q., Zhu, Y., Li, X., & Han, D. Adhesion Anisotropy Substrate with Janus Micropillar Arrays Guides Cell Polarized Migration and Division Cycle [J]. Angewandte Chemie,2019, 58(13), 4308-4312. 

     

    3 

    Feng, J., Sharma, S., Rao, E., Li, X., Zhang, Q., Liao, F.,Han, D& Rao, J.Stiffness heterogeneity-induced double-edged sword behaviors of carcinoma-associated fibroblasts in antitumor therapy[J]Science China. Materials,2019, 62(6), 873-884. 

     

    4 

    Cao, Y., Zhang, Y., Wang, Y., Liu, W., & Han, D.Improved stimulated echo in diffusion magnetic resonance imaging: introducing a pi pulse for SNR enhancement[J].Magnetic Resonance in Medicine,2019, 81(5), 2901-2914. 

                    https://onlinelibrary.wiley.com/cms/attachment/4f93d84c-90fe-4dc3-82eb-8acae975b780/mrm27653-fig-0001-m.jpg  

    5 

    Zhang Y., Nie Y., Zhu R., et al. Nitrogen doped carbon dots for turn-off fluorescent detection of alkaline phosphatase activity based on inner filter effect[J].Talanta, 2019: 74-81. 

    6 

    Sun, Q., Shi, X., Feng, J., Zhang, Q., Ao, Z., Ji, Y., & Han, D.Cytotoxicity and Cellular Responses of Gold Nanorods to Smooth Muscle Cells Dependent on Surface Chemistry Coupled Action[J]. Small,2018, 14(52). 

    7 

    Hu N., Cao Y., Ao Z., & Han, D.Flow behavior of liquid metal in the connected fascial space: Intervaginal space injection in the rat wrist and mice with tumor[J].Nano Research,2018, 11(4): 2265-2276. 

    8 

    Xu, X., Zhang, Q., Song, H., Ao, Z., Li, X., Cheng, C., & Han, D. Effects of artemisinin on ventricular arrhythmias in response to left ventricular afterload increase and microRNA expression profiles in Wistar rats[J]PeerJ,2018. 

     

    9 

    Zhu, Y., Sun, Q., Liu, Y., Ma, T., Su, L., Liu, S., Han, D & Liang, F. Decorating gold nanostars with multiwalled carbon nanotubes for photothermal therapy [J]. Royal Society Open Science,2018, 5(8). 

    10 

    Liu, S., Zhu, Y., Gao, H., Ge, P., Ren, K., Gao, J., Han, D & Zhang, J. One-step fabrication of functionalized poly(etheretherketone) surfaces with enhanced biocompatibility and osteogenic activity [J]. Materials Science and Engineering: C,2018, 70-78.

                   

     

    11 

    Gao, H., Zhao, Z., Cai, Y., Zhou, J., Hua, W., Chen, L., Han, D., Ming, J.& Jiang, L. Adaptive and freeze-tolerant heteronetwork organohydrogels with enhanced mechanical stability over a wide temperature range[J]Nature Communications,2017, 8(1). 

    12 

    Li, X., Liu, C., Chen, P., & Han, D. Micro-/Nano-Scale Biointerfaces, Mechanical Coupling and Cancer Therapy [J]. Current Topics in Medicinal Chemistry,2017, 17(16). 

    13 

    Han, X., Li, H., Hua, W., Dai, L., Ao, Z., Liao, F., & Han, D. Fluid in the tissue channels of vascular adventitia investigated by AFM and TEM[J]Clinical Hemorheology and Microcirculation,2017, 67(2), 173-182. 

    14 

    Li, Y., Shi, X., Tian, L., Sun, H., Wu, Y., Li, X., & Han, D. AuNP–Collagen Matrix with Localized Stiffness for CardiacTissue Engineering: Enhancing the Assembly of Intercalated Discs by β1IntegrinMediated Signaling [J]. Advanced Materials,2016, 28(46), 10230-10235.

                   

     

    15 

    Liu, C., Li, X., Hua, W., Li, J., Han, X., Ha, Q., & Han, D. Porous Matrix Stiffness Modulates Response to Targeted Therapy in Breast Carcinoma [J]. Small,2016, 12(34), 4675-4681. 

    16 

    Shi, X., Zhu, Y., Hua, W., Ji, Y., Ha, Q., Han, X., & Han, D. An in vivo study of the biodistribution of gold nanoparticles after intervaginal space injection in the tarsal tunnel [J]. Nano Research, 2016, 9(7), 2097-2109. 

    17 

    Li, X., Liu, C. Y., Li, Y. S., Xu, J., Li, D., & Han, D. Deep RNA sequencing elucidates microRNA-regulated molecular pathways in ischemic cardiomyopathy and nonischemic cardiomyopathy[J]Genetics and Molecular Research,2016, 15(2). 

     

    18 

    Liu, C., Li, X., Feng, J., Liao, F., Li, D., & Han, D. Substrate stiffness modulates mRNA expression profiling in breast cancer cells [J]. Clinical Hemorheology and Microcirculation,2016,63(4), 399-410. 

    19 

    Jiang, L., Sun, Z., Chen, X., Li, J., Xu,Y., Zu, Y., Hu,J., Han, D & Yang, C.Cells Sensing Mechanical Cues: Stiness in ?uences the Lifetime of Cell-Extracellular Matrix Interactions by Aecting the Loading Rate[J].ACS Nano, 2015, 10(1), 207-217. 

     

    20 

    Qin, M., Li, F., Huang, Y., Ran, W., Han, D & Song, Y. Twenty Natural Amino Acids Identification by a Photochromic Sensor Chip [J]. Analytical Chemistry,2015, 87(2), 837-842. 

     

    21 

    Feng, J., Lin, L., Chen, P., Hua, W., Sun, Q., Ao, Z., & Han, D. Topographical Binding to Mucosa-Exposed Cancer Cells: Pollen-Mimetic Porous Microspheres with Tunable Pore Sizes [J]. ACS Applied Materials & Interfaces,2015, 7(17), 8961-8967. 

    22 

    Chen L., Shi X., Li M., et al. Bioinspired photonic structures by the reflector layer of firefly lantern for highly efficient chemiluminescence [J].Scientific Reports, 2015, 5(1): 12965-12965. 

    23 

    Ding, Y., Cheng, Y., Sun, Q., Zhang, Y., You, K., Guo, Y.,Han, D& Geng, L. Mechanical characterization of cervical squamous carcinoma cells by atomic force microscopy at nanoscale[J]Medical Oncology, 2015, 32(3). 

    24 

    Jin, L., Guo, W., Xue, P., Gao, H., Zhao, M., Zheng, C. & Han, D. Quantitative assay for the colonization ability of heterogeneous bacteria on controlled nanopillar structures[J]. Nanotechnology,2015, 26(5), 055702. 

    25 

    Li, J., Hu, J., Feng, J., Han, D & Yang, C. Substrate stiffness of endothelial cells directs LFA-1/ICAM-1 interaction: A physical trigger of immune-related diseases[J].Clinical Hemorheology and Microcirculation,2015,61, 633-643. 

    26 

    Chen, P., Xu, L., Liu, J., Hol, F. J., Keymer, J. E., Taddei, F.,Han, D.,& Lindner, A. B. Nanoscale Probing the Kinetics of Oriented Bacterial Cell Growth Using Atomic Force Microscopy [J]. Small, 2014, 10(15), 3018-3025. 

     

    27 

    Ha, Q., Yang, G., Ao, Z., Niu, F., Han, D., & Wang, S. Rapid fibroblast activation in mammalian cells induced by silicon nanowire arrays[J]Nanoscale,2014, 6(14), 8318-8325. 

    28 

    Feng, J., Wang, F., Han, X., Ao, Z., Sun, Q., Hua, W., & Han, D. A “green pathway” different from simple diffusion in soft matter: Fast molecular transport within micro/nanoscale multiphase porous systems [J]. Nano Research,2014, 7(3), 434-442. 

    29 

    Gao, H., Zhang, J., Liu, F., Ao, Z., Liu, S., Zhu, S., Han, D. & Yang, B. Fabrication of polyaniline nanofiber arrays on poly(etheretherketone) to induce enhanced biocompatibility and controlled behaviours of mesenchymal stem cells[J]Journal of Materials Chemistry B,2014, 2(41), 7192-7200. 

    30 

    Sun, Q., Ao, Z., Feng, J., Li, H., & Han, D. Micro/-nanoscaled topography-coupled-mechanical action into functional biointerface [J]. Chinese Science Bulletin,2014, 59(28), 3523-3529. 

     

    31 

    Sun, M., Watson, G. S., Watson, J. A., Zheng, Y., Jiang, L., Han, D., & Liang, A. Wettability and adhesional differences on a natural template: the cicada wing [J]. Science of Advanced Materials,2014, 6(7), 1493-1500. 

    32 

    Li, J., Han, D., & Zhao, Y. Kinetic behaviour of the cells touching substrate: the interfacial stiffness guides cell spreading [J]. Scientific Reports,2014, 4(1). 

    33 

    Liu, H., Liu, X., Meng, J., Zhang, P., Yang, G., Su, B., Han, D. & Jiang, L. Hydrophobic InteractionMediated Capture and Release of Cancer Cells on Thermoresponsive Nanostructured Surfaces [J]. Advanced Materials,2013, 25(6), 922-927. 

    34 

    Liu, X., Chen, L., Liu, H., Yang, G., Zhang, P., Han, D. & Jiang, L. Bio-inspired soft polystyrene nanotube substrate for rapid and highly efficient breast cancer-cell capture[J]. Npg Asia Materials,2013, 5(9). 

    35 

    Li, J., Deng, Z., Chen, D., Ao, Z., Sun, Q., Feng, J. & Han, D. High-speed AFM for scanning the architecture of living cells[J]. Nanoscale, 2013, 5(18), 8355-8358. 

    36 

    Zhang, K., Feng, J., Sun, Q., Jin, L., Li, J., Wu, X., & Han, D. A multiple-labelling method for cells using Au nanoparticles with different shapes [J]. Chinese Science Bulletin,2013, 58(21), 2640-2645. 

    37 

    Chen, G., Zhao, L., Feng, J., You, G., Sun, Q., Li, P., .Han, D. & Zhou, H. Validation of Reliable Reference Genes for Real-Time PCR in Human Umbilical Vein Endothelial Cells on Substrates with Different Stiffness[J]. PLOS ONE,2013, 8(6). 

    38 

    Feng, J., Tang, Y., Xu, Y., Sun, Q., Liao, F., & Han, D. Substrate stiffness influences the outcome of antitumor drug screening in vitro [J]Clinical Hemorheology and Microcirculation,2013, 55(1), 121-131. 

    39 

    Liu, Y., Feng, J., Shi, L., Niu, R., Sun, Q., Liu, H. & Han, D. In situ mechanical analysis of cardiomyocytes at nano scales [J]. Nanoscale, 2012, 4(1), 99-102. 

    40 

    Han, D., & Liao, F. Chinese medicine, flowing blood, biomechanopharmacology and future preventive medicine [J]. Chinese Science Bulletin,2012, 57(27), 3541-3546. 

     

    41 

    Tian, S., Li, L., Sun, W., Xia, X., Han, D. & Gu, C. Robust adhesion of flower-like few-layer graphene nanoclusters[J]. Scientific Reports,2012, 2(1), 511-511. 

    42 

    Chen, G., Zhao, L., Liu, Y., Liao, F., Han, D. & Zhou, H. Regulation of blood viscosity in disease prevention and treatment [J]. Chinese Science Bulletin,2012, 57(16), 1946-1952. 

    43 

    Chen, L., Liu, X., Su, B., Li, J., Jiang, L., Han, D.& Wang, S. AptamerMediated Efficient Capture and Release of T Lymphocytes on Nanostructured Surfaces [J]. Advanced Materials,2011, 23(38), 4376-4380. 

     

    44 

    Chen, P., Jiang, L., & Han, D. In Situ Imaging of Multiphase Bio-interfaces at the Micro-/Nanoscale [J]. Small,2011, 7(20), 2825-2835. 

     

    45 

    Chen, L., Han, D., & Jiang, L. On improving blood compatibility: from bioinspired to synthetic design and fabrication of biointerfacial topography at micro/nano scales [J]. Colloids and Surfaces B: Biointerfaces,2011, 85(1), 2-7. 

    46 

    Deng, Y.,Sun, Q.,Ma, D.,Li, J., Han, D. &Li, D. Study on the microscaled mechanical properties and topography of exfoliated cervical cells [J].Journal of Chinese Electron Microscopy Society,2011. 

    47 

    Lin, L., Liu, M., Chen, L., Chen, P., Ma, J., Han, D., & Jiang, L. Bio-Inspired Hierarchical Macromolecule-Nanoclay Hydrogels for Robust Underwater Superoleophobicity[J]Advanced Materials,2010, 22(43), 4826-4830. 

     

    48 

    Heng, L., Tian, D., Chen, L., Su, J., Zhai, J., Han, D., & Jiang, L. Local photoelectric conversion properties of titanyl-phthalocyanine (TiOPc) coated aligned ZnO nanorods[J]Chemical Communications,2010, 46(7), 1162-1164. 

    49 

    Zhao, L., You, G., Liao, F., Kan, X., Wang, B., Sun, Q., Han, D. & Zhou, H. Sodium Alginate as Viscosity Modifier May Induce Aggregation of Red Blood Cells[J]Artificial Cells, Blood Substitutes, and Biotechnology,2010, 38(5), 267-276. 

    50 

    Shi, L., Shi, S., Li, J., Sun, Q., Feng, K., Chen, P. & Han, D. AFM and fluorescence imaging of nanomechanical response in periodontal ligament cells[J]Frontiers in Bioscience,2010, 2(1), 1028-1041. 

    51 

    Chen, L., Liu, M., Bai, H., Chen, P., Xia, F., Han, D., & Jiang, L. Antiplatelet and thermally responsive poly (N-isopropylacrylamide) surface with nanoscale topography[J]Journal of the American Chemical Society,2009, 131(30), 10467-10472. 

     

    52 

    Lao, F., Chen, L., Li, W., Ge, C., Qu, Y., Sun, Q., Han, D. & Chen, C. Fullerene Nanoparticles Selectively Enter Oxidation-Damaged Cerebral Microvessel Endothelial Cells and Inhibit JNK-Related Apoptosis[J]ACS Nano, 2009, 3(11), 3358-3368. 

     

    53 

    Fan, H., Chen, P., Qi, R. M., Zhai, J., Wang, J., Chen, L., Han, D. & Jiang, L.Greatly improved blood compatibility by microscopic multiscale design of surface architectures[J]Small,2009, 5(19), 2144-2148. 

     

    54 

    Chen, P., Chen, L., Zhai, J., Zheng, Y., Han, D. & Jiang, L. Wetting Behavior at Micro/Nanoscales: Direct Imaging of a Microscopic Water/Air/Solid ThreePhase Interface[J]Small,2009, 5(8), 908-912. 

    55 

    Mao, Y., Sun, Q., Wang, X., Ouyang, Q., Han, L., Jiang, L., & Han, D. In vivo nanomechanical imaging of blood-vessel tissues directly in living mammals using atomic force microscopy[J]Applied Physics Letters,2009, 95(1). 

    56 

    Chen, L., Chu, W., Xu, Y., Chen, P., Lao, F., Sun, Q. & Han, D. Timeseries investigation of fused vesicles in microvessel endothelial cells with atomic force microscopy[J]Microscopy Research and Technique,2009, 73(2), 152-159. 

    57 

    Lao, F., Li, W., Han, D., Qu, Y., Liu, Y., Zhao, Y., & Chen, C. Fullerene derivatives protect endothelial cells against NO-induced damage[J]. Nanotechnology, 2009, 20(22). 

    58 

    Ge G., Han D., Lin D., et al. MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue [J].Ultramicroscopy, 2007, 107(4): 299-307. 

    59 

    Li Y., Yuan B., Ji H., et al. A Method for Patterning Multiple Types of Cells by Using Electrochemical Desorption of Self-assembled Monolayers within Microfluidic Channels [J].Angewandte Chemie, 2007, 46(7): 1094-1096. 

    60 

    Sun T., Tan H., Han D., et al. No Platelet can adhere—Largely Improved Blood Compatibility on Nanostructured Superhydrophobic Surfaces [J].Small, 2005, 1(10): 959-963. 

        

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